Journal: Journal of Extracellular Vesicles
Article Title: Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?
doi: 10.1002/jev2.12052
Figure Lengend Snippet: NTA, TRPS, CLS, nFCM, AF4‐MALS and MADLS measurements of quadrimodal sample C (CPN100/CPN150/CPN200/CPN240 at 25/25/25/25). NTA, TRPS, nFCM and MADLS measurements were averaged over 3 runs and CLS over 2. AF4‐MALS was only performed once. The NTA inset shows the multi‐Gaussian fit of its PSD. The CLS inset shows the base‐line correction of the respective mass‐weighted PSD, whilst the AF4‐MALS inset shows the number density‐based fractogram and sample specific particle peak positions. The MADLS inset shows the intensity‐weighted PSD
Article Snippet: For this purpose, multi‐peak Gaussian fitting was applied, using Origin lab 9 software.
Techniques: